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Dicyclomine Hydrochloride IP
- Unit of Measure
We are famous amongst our customers as a trustworthy organization engaged in offering Dicyclomine Hydrochloride IP. This medications is ideal for treating a certain type of intestinal problem called irritable bowel syndrome. It helps to reduce the symptoms of stomach and intestinal cramping. This medication works by slowing the natural movements of the gut and by relaxing the muscles in the stomach and intestines. Dicyclomine Hydrochloride IP belongs to a class of drugs known as anticholinergics/antispasmodics. It is recommended to take this medication by mouth with or without food. This medicatioin must not be used in children younger than 6 months old.
Dicyclomine Hydrochloride IP/BP/USP Dicyclomine Hydrochloride is 2-diethylaminoethyl- bicyclohexyl-1-carboxylate hydrochloride
Formula: C19H35NO2, HCl
Mol. Wt.: 345.95
Dose: 30 to 60 mg daily, in divided doses. If used as an oral solution and the solution is required to be diluted, the diluted solution should be freshly prepared.
||White or almost white, crystalline powder; odourless or almost odourless.
||Freely soluble in ethanol (95%) and in chloroform; soluble in water; practically insoluble in ether.
||By infra-red absorption spectrum
||To 3 ml of a 0.1% w/v solution of sodium dodecyl sulphate, add 5 ml of chloroform and 0.05 ml of a 0.25% w/v solution of methylene blue, mix gently and allow to separate; the chloroform layer is blue. Add 20 mg of the substance being examined dissolved in 2 ml of water, mix gently and allow to separate; the aqueous layer is blue and the chloroform layer is colourless.
|C: Chloride Test||Dissolve 10 mg in 5 ml of water and add 0.2 ml of 2M nitric acid and 0.5 ml of silver nitrate solution; a white precipitate is produced.
|D: Melts||Between 172o and 174o.
||Any secondary spot in the chromatogram obtained with solution (1) is not more intense than the spot in the chromatogram obtained with solution (2).
||Not more than 0.1%.
|Loss on Drying
||Not more than 1.0%, determined on 1 g by drying in an oven at 105o
||Dicyclomine Hydrochloride contains not less than 99.0 per cent and not more than 101.0 per cent of C19H35NO2,HCl, calculated with reference to the dried substance.