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Dicyclomine Hydrochloride IP

Dicyclomine Hydrochloride IP
Dicyclomine Hydrochloride IP
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Product Code : DC
Brand Name : PALAM
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Product Description

We are famous amongst our customers as a trustworthy organization engaged in offering Dicyclomine Hydrochloride IP. This medications is ideal for treating a certain type of intestinal problem called irritable bowel syndrome. It helps to reduce the symptoms of stomach and intestinal cramping. This medication works by slowing the natural movements of the gut and by relaxing the muscles in the stomach and intestines. Dicyclomine Hydrochloride IP belongs to a class of drugs known as anticholinergics/antispasmodics. It is recommended to take this medication by mouth with or without food. This medicatioin must not be used in children younger than 6 months old.


Further Details:    

 

Dicyclomine Hydrochloride IP/BP/USP Dicyclomine Hydrochloride is 2-diethylaminoethyl- bicyclohexyl-1-carboxylate hydrochloride

Formula: C19H35NO2, HCl

Category: Antispasmodic.

Mol. Wt.: 345.95

Dose: 30 to 60 mg daily, in divided doses. If used as an oral solution and the solution is required to be diluted, the diluted solution should be freshly prepared.

Analysis
Specification
Description
White or almost white, crystalline powder; odourless or almost odourless.
Solubility
Freely soluble in ethanol (95%) and in chloroform; soluble in water; practically insoluble in ether.
Identification:
A:
By  infra-red absorption spectrum
B:
To 3 ml of a 0.1% w/v solution of sodium dodecyl sulphate, add 5 ml of chloroform and 0.05 ml of a 0.25% w/v solution of methylene blue, mix gently and allow to separate; the chloroform layer is blue. Add 20 mg of the substance being examined dissolved in 2 ml of water, mix gently and allow to separate; the aqueous layer is blue and the chloroform layer is colourless.
C: Chloride Test Dissolve 10 mg in 5 ml of water and add 0.2 ml of 2M nitric acid and 0.5 ml of silver nitrate solution; a white precipitate is produced.
D: Melts Between 172o and 174o.
Related Substances
Any secondary spot in the chromatogram obtained with solution (1) is not more intense than the spot in the chromatogram obtained with solution (2).
Sulphated Ash
Not more than 0.1%.
Loss on Drying
Not more than 1.0%, determined on 1 g by drying in an oven at 105o
Assay
Dicyclomine Hydrochloride contains not less than 99.0 per cent and not more than 101.0 per cent of C19H35NO2,HCl, calculated with reference to the dried substance.


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